During the covid19 pandemic, drosten came to national prominence as an expert on the implications and actions required to combat the outbreak in germany. Detection of 2019 novel coronavirus 2019ncov by realtime rt. Coronavirus nsp10, a critical cofactor for activation of. Christian drosten wikimili, the best wikipedia reader. During the 20192020 coronavirus pandemic, drosten came to national prominence as an expert on the implications and actions required to combat the outbreak in germany. Followup on diagnostic proficiency of laboratories.
Realtime rtpcr is widely deployed in diagnostic virology. Hoelscher, tobias bleicker, sebastian bruenink, julia schneider, rosina ehmann, katrin zwirglmaier, christian drosten, clemens wendtner. A n a n a l ysi s o f s a r s c o v 2 vi ra l l o a d b. Performance of the novel qiagen artus qsrgq viral load. Lassa virus may also be transmitted from human to human, which. Diagnostic detection of wuhan coronavirus 2019 by real. Coronavirus disease 2019 covid19 is an acute respiratory tract infection that emerged in late 20191,2. Virologe christian drosten zum coronavirus youtube.
Diagnostic detection of wuhan coronavirus 2019 by realtime. Dvv, german association for the control of virus diseases. An analysis of sarscov2 viral load by patient age terry c. Nicolas ruggli, ivi classical swine fever virus, a smart manipulator of the host 10. Corman, 4, 5 anna papa, 6 remi charrel, 7 christian drosten, 4, 5 marion koopmans, 2 katrin leitmeyer, 3 and on behalf of evdlabnet and erlinet 8.
Kerstin gnirss, daniela niemeyer, heike schneider, christian drosten, stefan pohlmann. Identification of a novel coronavirus in patients with severe acute respiratory syndrome. Christian drosten institute of virology university of bonn medical centre sigmund freudstr. Clinical presentation and virological assessment of hospitalized. Broberg, 3 bart haagmans, 2 adam meijer, 1 victor m. The natural host of lassa virus is the small rodent mastomys natalensis, which lives close to human settlements. The 148amino acid nsp10 subunit contains two zinc fingers and is known to interact with both nsp14 and nsp16, stimulating their respective 3. It is endemic in west africa and causes hemorrhagic fever in humans. In march 2003, a novel coronavirus sarscov was discovered in association with cases of severe acute respiratorysyndrome sars. Hospital wuhan institute of virology, chinese academy of sciences, china.
Daniela niemeyer this changed coronavirus eqa scheme will be preponed to spring 2020 and replaces the announced eqa scheme shipment of june 2020. Two years after the first external quality assurance study on bioterrorismrelevant viruses, we have conducted a followup study on orthopoxvirus detection by pcr. Christian heinrich maria drosten 1972, lingen ems is een duits viroloog. Evidence that tmprss2 activates the severe acute respiratory. Christian drosten, institute of virology, university of bonn medical centre d merscoronavirus ecology and epidemiology 10. Coronavirus update podcast mit virologe christian drosten. In june 1978, it was returned to the cas and renamed wuhan institute of virology. From 2007, drosten headed the institute of virology at university hospital bonn. Daniela niemeyer dear colleagues, below please find the table with the properties and expected qualitative results of samples 340059, 340060 and 340064 which are analyzed in the presently running instand external quality assessment eqa scheme 340 virus genome detection sarscov2. The program will have plenary sessions on themes that we feel will be informative and inspiring to virologists from all areas of expertise, as well as sessions for.
Christian drosten hat sarscov2 so gut erforscht wie kaum ein anderer. The quantifications correlated well for all hiv and hcv types, but qiagen yielded higher hcv concentrations than abbott, predominantly in genotypes 4 and 5. The sequence of the complete genome of sarscov was determined, and the initial characterization of the viral genome is presented in this report. Crimeancongo hemorrhagic fever cchf is a severe viral disease transmitted to humans by tick bite or contact with blood. Kindergarten kg, grade school gs, highschool hs, etc. Samples contained 0 to 40,000,000 dna copies of lyophilized monkeypox, cowpox, and vaccinia virus per ml. Christian heinrich maria drosten born 1972 is a german virologist whose research focus is on novel viruses emergent viruses. Characterization of a novel coronavirus associated with. A n a n a l ysi s o f s a r s c o v 2 vi ra l l o a d b y p a t i e n t a g e t e rry c. Jones 1,2, barbara muhlemann 1,3, talitha veith 1,3, marta zuchowski 4, jorg hofmann 4, angela stein 4, anke edelmann 4, victor max corman 1,3, christian drosten 1,3 affiliations.
Christian heinrich maria drosten born 1972 in lingen is a german virologist whose research focus is on novel viruses emergent viruses. Duitsland bereidt zich voor op tweede, zwaardere golf van coronavirus. We compared two novel qiagen qsrgq viral load assays with the established abbott realti m e assays on a highly diversified panel of 121 human immunodeficiency virus hiv and 107 hepatitis c virus hcv specimens. Lassa virus is a negativestrand rna virus that belongs to the family arenaviridae. Virological assessment of hospitalized patients with covid2019. No significant difference between children and adults. Improved detection of lassa virus by reverse transcription. The children are of an analysis in germany, according to the present coronavirus pandemic, probably as contagious as adults. Viral load and crimeancongo hemorrhagic fever to the editor.
Joint meeting of the german research platform for zoonoses and the research network of zoonotic infectious diseases martin h. Drexler jf, glozarausch f, glende j, corman vm, muth d, goettsche m, et al. Laboratory readiness and response for novel coronavirus. Christian drosten is head of the institute of virology at the university of bonn medical centre, one of germanys largest medical virology centres. Thirtythree laboratories 27 european, 4 australasian, and 2 american participated. The rnasynthesizing machinery of the severe acute respiratory syndrome coronavirus sarscov is composed of 16 nonstructural proteins nsp116 encoded by orf1a1b. University hospital lmu munich, munich, germany camilla rothe, m. Christian heinrich maria drosten born 1972 is a german virologist whose research focus is. Program program we aim to convene scientists from across the virosphere, ranging from basic to clinical virology, mixing medical, veterinary, wildlife, invertebrate and plant virology. Program registration still for eqa term june 2020 shipment date of the preponed eqa scheme.
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